The completion of the human genome was just the beginning of the search to understand our own genetic underpinnings. Since that time, researchers, including those at the McDonnell Genome Institute, have continued to scrutinize the human genome in many ways — from describing the structure and function of our sex chromosomes (X,Y) to deciphering the immense variation present among human and mammalian populations.
In 2008, the McDonnell Genome Institute became the first to sequence the complete genome of a cancer patient — a woman with leukemia — and to trace her disease to its genetic roots.
To better understand and help develop new treatments and therapies, the McDonnell Genome Institute is sequencing and analyzing genomes associated with diseases such as cancer that affect populations around the world.
See below for a list of our collaborative genomics projects.
Collaborative large-scale genome sequencing effort comprehensively identifying rare risk and protective variants that contribute to common disease phenotypes
Improving the sequence quality and accuracy of the human reference genome
St. Jude Children’s Research Hospital and MGI teamed up to decode the genomes of more than 600 childhood cancer patients
The McDonnell Genome Institute is committed to enhancing and diversifying human reference genomes.
A comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer