Our lab focuses on two main areas, taking advantage of next-generation genomic and computational approaches to empower the study of infectious diseases and the human microbiome. We have had and hope to continue fruitful collaborations with collaborators from around the world so that we can together make a lasting contribution to both understanding diseases at a molecular level and improving clinical practices to treat them.
Infectious diseases: Parasites, bacteria, viruses, fungi
We have a sustained commitment to extending genomics for infectious agents (parasites, fungi, bacteria and viruses) by generating reference genomes and sequencing clinical/field isolates related to a specific phenotype. Our multi-omics approaches are revolutionizing the filed of infectious diseases and our work intends to translates basic science advances in genomics into practical knowledge that contributes to control or elimination of infectious diseases.
Some areas of interest include:
- Genomes and evolution
- Gene expression and regulation
- Antigen discovery
- Host response
- Drug targets
- Population genomics
- Databases and analysis tools
The Mitreva lab receives funding from the following sources:
- National Institute of Allergy and Infectious Diseases (NIAID)
- National Human Genome Research Institute (NHGRI)
- National Institute of General Medical Sciences (NIGMS)
- U.S. Department of Agriculture – National Institute of Food & Agriculture (USDA – NIFA)
- National Science Foundation (NSF)
- Bill & Melinda Gates Foundation
- Burroughs Wellcome Fund
- National Institutes of Health (NIH)
The Mitreva lab is a member of the Center for Clinical Genomics of Microbial Systems CC-GEMS, a collaboration involving MGI and the Departments of Pediatrics and Medicine at Washington University. More information is available at CC-GEMS.
Mitreva lab projects
- Human Microbiome: A catalog of genetic information with the microbes in and on the human body that contribute to our survival.