We conduct biological research in the realms of genetics, genomics and bioinformatics. Broadly speaking, we use a combination of high-throughput experimental and computational methods to study the causes and consequences of genome variation in mammals. Recent projects involve diverse topics including human and statistical genetics, bioinformatics tools development, genome structural variation, genetic mosaicism, tumor evolution and single cell genomics. Most of our ongoing work is focused on the application of human genome sequencing and integrative data science approaches to identify the genetic origins of medically relevant human traits.
Dr. Hall is co-leader of the NHGRI-funded MGI Center for Common Disease Genomics, which is conducting population-scale genome sequencing studies to identify genetic factors that confer risk or protection for various complex human diseases in the broader cardiovascular, autoimmune and neuropsychiatric disease areas.
For job opportunities in the Hall lab, please see Careers page.
Hall lab projects
- Genome Reference Consortium: Improving the sequence quality and accuracy of the human reference genome.
- Center for Common Disease Genomics: Collaborative large-scale genome sequencing effort comprehensively identifying rare risk & protective variants that contribute to common disease phenotypes.