Washington University pumps millions into Cortex building, as another rises nearby

Washington University is investing millions of dollars in a decades-old building near Cortex, helping boost occupancy there as another 11-story research development rises nearby. The university last summer completed renovations to the McDonnell Genome Institute and Genome Technology Access Center, both at 4444 Forest Park Ave. And more work, including a genome engineering center and […]

Photos: Washington U. School of Med. deploys COVID saliva testing

Washington University School of Medicine, using a $5 million grant from the National Institutes of Health, has begun administering the COVID-19 saliva test it developed in the Special School District of St. Louis County in search of asymptomatic carriers among teachers initially. The test, which is reportedly 99% accurate, is distributed weekly on a voluntary […]

Podcast: The making of a fast, accurate saliva test for COVID-19

A new episode of our podcast, “Show Me the Science,” has been posted. At present, these podcast episodes are highlighting research and patient care on the Washington University Medical Campus as our scientists and clinicians confront the COVID-19 pandemic.

WUSTL-led Team Compiles Human Structural Variant Resource

“A team led by Washington University in St. Louis researchers has profiled rare and ultra-rare structural variants in nearly 18,000 high-coverage whole-genome sequences in an effort to fill in remaining gaps in the understanding of the larger variants that impact protein-coding and non-coding portions of the genome.”

$5 million supports research into neglected tropical diseases

“Led by Makedonka Mitreva, PhD, a professor of medicine and of genetics, both projects involve large-scale genome sequencing of the parasites to develop genetic tools to help monitor the infections’ spread and track resistance these parasites already have developed against drugs intended to eradicate them. “ https://medicine.wustl.edu/news/5-million-supports-research-into-neglected-tropical-diseases/

School of Medicine physicians, researchers tackle coronavirus

Clinical teams ready; research for vaccines, drugs underway “geneticist Ting Wang, PhD, the Sanford and Karen Loewentheil Distinguished Professor of Medicine, and members of his lab built a genome browser to help researchers study the genetics of the COVID-19 virus and compare different strains.”

Personal toll

Mother’s death sets twin scientists on journey to find precision cancer therapies

Immune responses to tuberculosis mapped across 3 species

A detailed genetic road map will guide research into TB treatments, vaccines. This work and article features co-senior author Makedonka Mitreva, PhD, a professor of medicine and of genetics at Washington University and a researcher at the university’s McDonnell Genome Institute.

Kingdom Capital Collaborates with Washington University School of Medicine to Launch Augmented Intelligence Company PercayAI

– PercayAI, launched by Kingdom Capital, represents the investment firm’s commitment to cultivating new technologies that can help accelerate drug discovery and improve patient outcomes – Washington University School of Medicine in St. Louis will continue to develop technology that will be commercialized through PercayAI as part of an ongoing collaboration with Kingdom Capital

NHGRI funds centers for advancing the reference sequence of the human genome

New grants totaling approximately $29.5 million will enable scientists to generate and maintain the most comprehensive reference sequence of the human genome. The awards, made over five years pending the availability of funds, are managed by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health.

Academy of Science-St. Louis honors faculty

Dutcher received a 2019 George Engelmann Interdisciplinary Award, which recognizes outstanding achievement in science, engineering or technology that results from collaboration among two or more individuals across disciplinary or institutional boundaries.

Five inducted into Bouchet Graduate Honor Society

Five PhD candidates at Washington University in St. Louis were inducted into the Edward A. Bouchet Graduate Honor Society at the annual Bouchet Conference on Diversity and Graduate Education April 5-6 at Yale University.

Quantum leap in parasite worm treatment research

Parasitic roundworms & flatworms (helminths) cause some of the most common yet neglected tropical infectious diseases affecting more than 1B people worldwide.

Genes linked to Alzheimer’s contribute to damage in different ways

Multiple genes are implicated in Alzheimer’s disease. Some are linked to early-onset Alzheimer’s, a condition that develops in one’s 30s, 40s and 50s, while others are associated with the more common late-onset form of the disease.

Genetic testing helps predict disease recurrence in myelodysplastic syndrome

A DNA-based analysis of blood cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients with myelodysplastic syndrome (MDS), a group of cancerous disorders characterized by dysfunctional blood cells, according to new research at WU and MGI. Such a practice could help doctors identify patients at high risk of disease recurrence early after a transplant and help guide treatment decisions. The study is published Sept. 13 in The New England Journal of Medicine.

10X Genomics Hosts 2018 Symposium at WashU

10X Genomics had its first single cell user group meeting at Washington University on Tuesday August 28, 2018. The symposium took place at Eric P. Newman Center from 9-4 and was filled with speakers, software demonstrations, discussions, and networking. Ranging from various disciplines and departments, speakers from Washington University included Dr. Benjamin Humphreys (Renal), Dr. Allegra Petti […]

MGI Cohosts Upcoming 2018 PacBio Meeting September 19-20

The McDonnell Genome Institute is proudly collaborating with PacBio Sequencing to host its first user group meeting at Washington University on Wednesday September 19-20, 2018. The event will take place at the Eric P. Newman Center located on Washington University Medical School Campus. The event will offer the opportunity to explore new scientific content through […]

Analysis of prostate tumors reveals clues to aggressiveness

Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common. The study lays the foundation for finding new ways to treat prostate cancer, particularly for the most aggressive forms of the disease.

Funded Pilot Project

The McDonnell Genome Institute at (MGI) has awarded 9 pilot project grants to support novel collaborations with WU investigators. A committee of 5 faculty members reviewed the 48 submissions from a variety of departments and awarded nine grants.  Luigi Adamo, Kory Lavine, Douglass Mann – Cardiology Characterization of myocardial B cells heterogeneity and clonal expansion […]

Dutcher Elected 2017 AAAS Fellow

Susan Dutcher, PhD, a professor of genetics and the interim director of The McDonnell Genome Institute at Washington University School of Medicine in St. Louis, has been named a 2017 fellow of the American Society for Cell Biology (ASCB).

Washington University receives $10 million for DNA sequencing research

The McDonnell Genome Institute at Washington University School of Medicine in St. Louis will receive $60 million from the National Institutes of Health (NIH) to study the genetics of common diseases, such as heart disease, diabetes, stroke, autism and epilepsy.