The Elizabeth H. and James S. McDonnell III Genome Institute provides comprehensive genomic services to Washington University and the scientific community.
Leading the way in high-speed, comprehensive genomics.
We aim to improve the human condition by producing, studying and interpreting high-quality genome-based data that drives biological discoveries.
A Team of Experts
Li Ding, PhD, led a team that analyzed DNA from nearly 10,000 patient tumors across 33 cancer types. They found 300 genes that drive cancer, and more than half of the tumors analyzed had at least one mutation of clinical significance.
Over $1.3B in Research Funding
The McDonnell Genome Institute has received over $1.3 billion in research funding to inform future clinical work and help in the study, diagnosis and treatment of disease.
Latest News
Quantum leap in parasite worm treatment research with largest ever helminth genome study
Parasitic roundworms and flatworms (collectively known as “helminths”) cause some of the most common yet neglected tropical infectious diseases affecting more than a billion people worldwide, in addition to afflicting many important plants and animals.
Relapsed leukemia flies under immune system’s radar
Researchers at Washington University School of Medicine in St. Louis have shown one way relapsed leukemia cells evade the immune system. They further identified a possible way to reverse the cancer's evasive maneuvers. The study's co-first authors are Michael Rettig, Allegra Petti and Matthew Christopher, MD, PhD.
Genes linked to Alzheimer’s contribute to damage in different ways
Multiple genes are implicated in Alzheimer’s disease. Some are linked to early-onset Alzheimer’s, a condition that develops in one’s 30s, 40s and 50s, while others are associated with the more common late-onset form of the disease.