The Elizabeth H. and James S. McDonnell III Genome Institute provides comprehensive genomic services to Washington University and the scientific community.

Leading the way in high-speed, comprehensive genomics.

We aim to improve the human condition by producing, studying and interpreting high-quality genome-based data that drives biological discoveries.

A Team of Experts


Li Ding, PhD, led a team that analyzed DNA from nearly 10,000 patient tumors across 33 cancer types. They found 300 genes that drive cancer, and more than half of the tumors analyzed had at least one mutation of clinical significance.

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Over $1.3B in Research Funding


The McDonnell Genome Institute has received over $1.3 billion in research funding to inform future clinical work and help in the study, diagnosis and treatment of disease.

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Latest News


WUSTL-led Team Compiles Human Structural Variant Resource

“A team led by Washington University in St. Louis researchers has profiled rare and ultra-rare structural variants in nearly 18,000 high-coverage whole-genome sequences in an effort to fill in remaining gaps in the understanding of the larger variants that impact protein-coding and non-coding portions of the genome.”
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