McDonnell Genome Institute

Elizabeth H. and James S. McDonnell III Genome Institute

World leader in the fast-paced, constantly changing field of genomics

Our Mission

To unveil the secrets of the genome,

the blueprint of life,

to improve the lives of people everywhere

Genome Technology
Access Center
(GTAC@MGI)

GTAC@MGI provides cutting-edge, cost-effective sequencing, and analysis technologies to collaborators. We are committed to generating the highest quality data and providing excellent value-added services and resources.

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Genome Editing and
iPSC Center
(GEiC@MGI)

GEiC@MGI facilitates collaborators and customers with functional genomic studies through the use of patient-derived iPSCs and the generation of modified cells and organisms using genome editing technologies.

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Innovative Research

Since its inception in 1993, the McDonnell Genome Institute has played a vital role in the field of genome sequencing, receiving over $1.3 billion in research funding. Today, MGI has taken the COVID-19 Pandemic head on by developing a saliva based test to help detect who has contracted the illness

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Strong Leadership

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Latest News

Whole-Genome Sequencing Could Replace Cytogenetics in Assessing AML, Myelodysplastic Syndromes (Links to an external site)

April 6, 2021

Mar 11, 2021 | staff reporter NEW YORK — Whole-genome sequencing could serve as an alternative to cytogenetic analysis for acute myeloid leukemia or myelodysplastic syndromes, a new study has found.

Finnish Cardiometabolic Study Uncovers Strong Effect of Structural Variants (Links to an external site)

March 25, 2021

Mar 23, 2021 | staff reporter NEW YORK – Using genetic data for thousands of individuals from the Finnish population, an international team has tracked down more than a dozen loci linked to cardiometabolic traits, including two previously unappreciated structural variant (SV) sites that appear to have particularly strong ties to specific traits.

Mitochondrial Phenotypes Distinguish Pathogenic MFN2 Mutations by Pooled Functional Genomics Screen (Links to an external site)

March 15, 2021

Alex L Yenkin, John C Bramley, Jason E Waligorski, Colin L Kremitzki, Mariel J Liebeskind, Xinyuan E Xu, Maria A Vakaki, Vinay Chandrasekaran, Robi David Mitra, Jeffrey D Milbrandt, William J Buchser MGI identified subtle mitochondrial phenotypes & physically captured individual cells with single point mutations.

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