The Elizabeth H. and James S. McDonnell III Genome Institute provides comprehensive genomic services to Washington University and the scientific community.
Leading the way in high-speed, comprehensive genomics.
We aim to improve the human condition by producing, studying and interpreting high-quality genome-based data that drives biological discoveries.
A Team of Experts
The McDonnell Genome Institute team makes use of genetics, genomics and bioinformatics approaches to achieve the following:
- Develop personalized medicine tools and strategies
- Better understand cancer, infectious and other diseases
- Enhance knowledge of biodiversity among all living organisms
- Promote diversity in STEM (science, technology, engineering, mathematics) research
Over $1.3B in Research Funding
The McDonnell Genome Institute has received over $1.3 billion in research funding to inform future clinical work and help in the study, diagnosis and treatment of disease.
Latest News
Whole-Genome Sequencing Could Replace Cytogenetics in Assessing AML, Myelodysplastic Syndromes (Links to an external site)
Mar 11, 2021 | staff reporter NEW YORK — Whole-genome sequencing could serve as an alternative to cytogenetic analysis for acute myeloid leukemia or myelodysplastic syndromes, a new study has found.
Finnish Cardiometabolic Study Uncovers Strong Effect of Structural Variants (Links to an external site)
Mar 23, 2021 | staff reporter NEW YORK – Using genetic data for thousands of individuals from the Finnish population, an international team has tracked down more than a dozen loci linked to cardiometabolic traits, including two previously unappreciated structural variant (SV) sites that appear to have particularly strong ties to specific traits.
Mitochondrial Phenotypes Distinguish Pathogenic MFN2 Mutations by Pooled Functional Genomics Screen (Links to an external site)
Alex L Yenkin, John C Bramley, Jason E Waligorski, Colin L Kremitzki, Mariel J Liebeskind, Xinyuan E Xu, Maria A Vakaki, Vinay Chandrasekaran, Robi David Mitra, Jeffrey D Milbrandt, William J Buchser MGI identified subtle mitochondrial phenotypes & physically captured individual cells with single point mutations.
