Salmonella enterica subspecies IIIa (Arizonae) serovar 62:z4,z23:--
Salmonella Arizonae
Habitat
Most bacteria in the species S. enterica belong to one of seven subspecies; all but subspecies I normally grow only in cold-blooded animals. Subspecies IIIa (S. Arizonae) is naturally found in reptiles, but also causes outbreaks of salmonellosis in turkeys and sheep and can occasionally produce both gastroenteritis and serious disseminated disease in humans. Many human infections can be traced to contact with reptiles or ingestion of various reptile products, particularly from rattlesnakes. Fewer than ten cases in humans are typically reported in the US each year.
Biology
Salmonella is a Gram-negative bacterium, a cylindrical rod of size about 2 microns by 0.5 microns, thus much smaller than the cells of higher organisms such as humans. In culture, the bacterium will grow on artificial media to form colonies. Subspecies IIIa (also called Arizonae) is monophasic for flagellar synthesis, i.e., it makes only one type of flagellum.
Sequencing Plan
The strain of S. enterica var Arizonae (62:z4,z23:-) sequenced is CDC346-86; it was named RSK2980 by R.K. Selander and is strain SARC5 of the Salmonella Reference C set. This serovar is of interest because of its taxonomic position. It appears to be the most divergent subspecies among the S. enterica. It can be obtained from the American Type Culture Collection as ATCC BAA-731, or the Salmonella Genetic Stock Centre as SGSC4693. The genome was sequenced to 8X coverage, using plasmid and fosmid libraries, and was finished to an error rate of less than 1 per 10,000 bases. Automated annotation was performed and manual annotation continued in the labs of Michael McClelland and Kenneth Sanderson. The completed sequence is available from GenBank (CP000880.1). The National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH) has funded this project.
Contacts
| Name | Affiliation |
|---|---|
| Patrick Minx | The Genome Institute, Washington University School of Medicine |
| Michael McClelland | Cancer Genetics Program, Sidney Kimmel Cancer Center |
| Kenneth Sanderson | Salmonella Genetic Stock Centre, University of Calgary |
Sequences & Maps
Assemblies
| Name | Date | Description | Blast DBs |
| Salmonella_enterica_serovar_Arizonae-1.0 | Dec 06, 2005 | 8.7X | contigs supercontigs |
| Salmonella_enterica_serovar_Arizonae-3.0 | Feb 02, 2006 | 8.5X | supercontigs contigs |
| Salmonella_enterica_serovar_Arizonae-4.0 | Mar 02, 2006 | 8.6X | contigs supercontigs |
