Saccharomyces Genome Sequencing at TGI
With the goal of identifying functional non-coding DNA sequences in the yeast genome, we have partially determined the genome sequences (2 to 4-fold shotgun coverage) of five Saccharomyces species (click here for a phlyogenetic tree of these species):
- S. mikatae
- S. kudriavzevii
- S. bayanus
- S. castellii
- S. kluyveri
Finding functional features in Saccharomyces Genomes by phylogenetic footprinting
The first three species listed above are relatively closely related to S. cerevisiae, and the alignments of their sequences to S. cerevisiae sequence are likely to be most useful for identifying conserved non-coding sequences. The last two species listed above are more distantly related to S. cerevisiae, so alignments of S. cerevisiae protein sequences to their orthologs in these species are likely to be more useful for identifying possible functional domains in protein sequence.
The sequences in this database are incomplete. They consist of unedited contigs assembled from "shotgun" sequencing reads. Sequencing errors and misassembles undoubtedly exist in the data. We are in the process of finishing portions of the sequence, and will correct some errors in the data as we discover them, but much of the data is likely to remain unedited.
