Wes Warren, Ph.D. |
Wes Warren, Ph.D.
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Assistant Director, Genome Sequencing Center
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| Research Accomplishments & Interests |
I have over 12 years of experience in the biopharmaceutical industry and have managed numerous product development projects. I previously served as group manager of genome initiatives at Monsanto Company, Senior Director of Operations at Incyte Genomics, Director of the Microarray Core Facility at the Genome Sequencing Center (GSC), Washington University School of Medicine and most recently I serve as Assistant Director of the GSC, Washington University School of Medicine.
As Assistant Director of the Genome Sequencing Center, I assist with the team based selection process for the whole genome sequencing of various species. In addition, I serve as Director of Mapping at the GSC in which I supervise a group that specializes in the construction of whole genome physical maps, sequence gap closure in select species and the selection of clones which serve as a minimum representation of the genome for further experimentation. This group has been responsible for providing these critical resources to the community for several model organisms in addition to human.
I have an active interest in the use of genome architecture methods to study genome aberrations, particularly balanced translocations pertinent to cancer origin. The identification of these chromosomal translocations promise to engender new therapeutic interventions for cancer.
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| Selected Publications: |
Wallis et al. 2004. A physical map of the chicken genome. Nature 432:761-764.
Kryzwinski, M. et al. 2004. Integrated and sequence-ordered BAC- and YAC-based physical maps for the rat genome. Genome Res. 14: 766-779.
McClelland M. et al. 2004. Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid. Nat Genet. 36:1268-1274.
International Chicken Genome Sequencing Consortium. 2004. Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature. 432:695-716.
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